Fatty acid composition and biological activities of seed oil from rubber (Hevea brasiliensis) cultivar RRIM 600
Summary. The oils from seeds of Hevea brasiliensis (Muëll. Arg.) cultivar RRIM 600 cultivated in Thailand (from two different sources, Chiang Rai and Surin provinces), were subjected to the evaluation of fatty acid composition, antioxidant activities, antimicrobial activities and cytotoxicity. The seed oils were extracted using n-hexane as a solvent and the major fatty acids were oleic and linoleic acids. The seed oils from two different sources similarly exhibited high capability in inhibiting scavenging DPPH radicals (95%, 87% inhibition, from Chiang Rai and Surin provinces respectively), reducing power (1.588±0.016, 1.832±0.009 mg of AAE/mL). However, moderate lipid peroxidation inhibition activity of these two seed oils were observed (24%, 28% inhibition). The cytotoxicity effect of oil was determined on human dermal fibroblast. It showed that the H. brasiliensis seed oil was not cytotoxic to human skin at >1000 μg/mL. Based on these results, it was suggested that the H. brasiliensis seed oil may be considered as a potential antioxidant candidate for topical cosmetic applications.
Industrial relevance. Natural origin raw materials have gained increasing attention for cosmetics because of their effectiveness and safety as compared to the synthetics. H. brasiliensis seed oil from this research has shown itself as a highly promising natural raw material source for cosmetic industry. It composed of skin health benefit fatty acids and has been found to exhibit high capability in inhibiting scavenging DPPH radicals. Moreover, from the cytotoxicity result, it indicated that the H. brasiliensis seed oil can safely be applied to human skin.
Keywords. Hevea brasiliensis; seed oil; fatty acids; biological activities
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